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Women's Health HRT May Treat Symptoms, but Shorten Life Short-term hormone replacement therapy can increase quality of life but shorten life expectancy for some menopausal women, U.S. researchers said. An article in The Archives of Internal Medicine, published Tuesday by the American Medical Association, said researchers at Rhode Island Hospital in Providence developed a computer model that showed among women without any symptoms of menopause, short-term HRT was linked with overall decreases in life expectancy and quality-adjusted life expectancy of one to three months. Women with mild menopausal symptoms gained three to four months of quality-adjusted life expectancy, and those with severe symptoms gained seven to eight months if quality-adjusted expectancy, researchers said. The model, based on findings from the Women's Health Initiative, a large clinical hormone therapy trial, simulates the effects of hormone therapy use for two years among 50-year-old menopausal women. Hormone therapy is effective for menopausal symptoms and decreases risks of osteoporosis and colorectal cancer, but it also can increase the risk of coronary heart disease, stroke and breast cancer, researchers said. Copyright 2004 by United Press International. All rights reserved. - Updated: August 17, 2004 |
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